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A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene
Genome-wide association studies have identified more than 200 genetic variants to be associated with an increased risk of developing multiple sclerosis (MS). Still, little is known about the causal molecular mechanisms that underlie the genetic contribution to disease susceptibility. In this study,...
Autores principales: | Hecker, Michael, Boxberger, Nina, Illner, Nicole, Fitzner, Brit, Schröder, Ina, Winkelmann, Alexander, Dudesek, Ales, Meister, Stefanie, Koczan, Dirk, Lorenz, Peter, Thiesen, Hans-Jürgen, Zettl, Uwe Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382214/ https://www.ncbi.nlm.nih.gov/pubmed/30730892 http://dx.doi.org/10.1371/journal.pgen.1007961 |
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