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Prediction of Driver Modules via Balancing Exclusive Coverages of Mutations in Cancer Samples

Mutual exclusivity of cancer driving mutations is a frequently observed phenomenon in the mutational landscape of cancer. The long tail of rare mutations complicates the discovery of mutually exclusive driver modules. The existing methods usually suffer from the problem that only few genes in some i...

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Detalles Bibliográficos
Autores principales: Gao, Bo, Zhao, Yue, Li, Yang, Liu, Juntao, Wang, Lushan, Li, Guojun, Su, Zhengchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382311/
https://www.ncbi.nlm.nih.gov/pubmed/30828525
http://dx.doi.org/10.1002/advs.201801384