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Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models

Spinocerebellar ataxia (SCA) type 17 is an autosomal dominant ataxia caused by expanded polyglutamine (polyQ) tract in the TATA-box binding protein (TBP). Substantial studies have shown involvement of compromised mitochondria biogenesis regulator peroxisome proliferator-activated receptor gamma-coac...

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Detalles Bibliográficos
Autores principales: Chen, Chiung-Mei, Chen, Wan-Ling, Hung, Chen-Ting, Lin, Te-Hsien, Lee, Ming-Chung, Chen, I-Cheng, Lin, Chih-Hsin, Chao, Chih-Ying, Wu, Yih-Ru, Chang, Kuo-Hsuan, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382417/
https://www.ncbi.nlm.nih.gov/pubmed/30760647
http://dx.doi.org/10.18632/aging.101804