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Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models
Spinocerebellar ataxia (SCA) type 17 is an autosomal dominant ataxia caused by expanded polyglutamine (polyQ) tract in the TATA-box binding protein (TBP). Substantial studies have shown involvement of compromised mitochondria biogenesis regulator peroxisome proliferator-activated receptor gamma-coac...
Autores principales: | Chen, Chiung-Mei, Chen, Wan-Ling, Hung, Chen-Ting, Lin, Te-Hsien, Lee, Ming-Chung, Chen, I-Cheng, Lin, Chih-Hsin, Chao, Chih-Ying, Wu, Yih-Ru, Chang, Kuo-Hsuan, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382417/ https://www.ncbi.nlm.nih.gov/pubmed/30760647 http://dx.doi.org/10.18632/aging.101804 |
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