AluYb8 insertion polymorphism in the MUTYH gene impairs mitochondrial DNA maintenance and affects the age of onset of IPF

Background: Idiopathic pulmonary fibrosis (IPF) is an age-related fatal disease with an unknown etiology. Increased oxidative stress and mitochondrial dysfunction are thought to be involved in its pathogenesis. However, the effect of the AluYb8MUTYH polymorphism on IPF is not known. Results: The mea...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Sun, Jiapeng, Guo, Wenwen, Zhuang, Yi, Xu, Lizhi, Wang, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382421/
https://www.ncbi.nlm.nih.gov/pubmed/30716719
http://dx.doi.org/10.18632/aging.101793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382421/
https://www.ncbi.nlm.nih.gov/pubmed/30716719
http://dx.doi.org/10.18632/aging.101793

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