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Preparation of Recombinant Alphaviruses for Functional Studies of ADP-Ribosylation
Recently we characterized the mono(ADP-ribosyl) hydrolase (MAR hydrolase) activity of the macrodomain of nonstructural protein 3 (nsP3(MD)) of chikungunya virus. Using recombinant viruses with targeted mutations in the macrodomain, we demonstrated that hydrolase function is important for viral repli...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382469/ https://www.ncbi.nlm.nih.gov/pubmed/30097877 http://dx.doi.org/10.1007/978-1-4939-8588-3_21 |