Increased Ratio of Global O-GlcNAcylation to Tau Phosphorylation at Thr212 Site Is Associated With Better Memory Function in Patients With Type 2 Diabetes

Objective: Aberrant O-GlcNAc modification has been implicated in type 2 diabetes mellitus (T2DM) and the pathogenesis of neurodegenerative diseases via competition with tau phosphorylation. We aimed to investigate the association between global O-GlcNAcylation, tau phosphorylation levels and mild co...

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Detalles Bibliográficos
Autores principales: Huang, Rong, Tian, Sai, Han, Jing, Cai, Rongrong, Lin, Hongyan, Guo, Dan, Wang, Jiaqi, Wang, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382671/
https://www.ncbi.nlm.nih.gov/pubmed/30837891
http://dx.doi.org/10.3389/fphys.2019.00110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382671/
https://www.ncbi.nlm.nih.gov/pubmed/30837891
http://dx.doi.org/10.3389/fphys.2019.00110

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