The CagRS Two-Component System Regulates Clavulanic Acid Metabolism via Multiple Pathways in Streptomyces clavuligerus F613-1

Streptomyces clavuligerus F613-1 produces a clinically important β-lactamase inhibitor, clavulanic acid (CA). Although the biosynthesis pathway of CA has essentially been elucidated, the global regulatory mechanisms of CA biosynthesis remain unclear. The paired genes cagS and cagR, which are annotat...

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Detalles Bibliográficos
Autores principales: Fu, Jiafang, Qin, Ronghuo, Zong, Gongli, Liu, Cheng, Kang, Ni, Zhong, Chuanqing, Cao, Guangxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382702/
https://www.ncbi.nlm.nih.gov/pubmed/30837970
http://dx.doi.org/10.3389/fmicb.2019.00244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382702/
https://www.ncbi.nlm.nih.gov/pubmed/30837970
http://dx.doi.org/10.3389/fmicb.2019.00244

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