Multi-Substrate Specificity and the Evolutionary Basis for Interdependence in tRNA Editing and Methylation Enzymes

Among tRNA modification enzymes there is a correlation between specificity for multiple tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved residue in different tRNA sequences adopt a heterodimeric structure. Presumably, such changes in the oligomeric state of enzy...

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Detalles Bibliográficos
Autores principales: Dixit, Sameer, Henderson, Jeremy C., Alfonzo, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382703/
https://www.ncbi.nlm.nih.gov/pubmed/30838029
http://dx.doi.org/10.3389/fgene.2019.00104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382703/
https://www.ncbi.nlm.nih.gov/pubmed/30838029
http://dx.doi.org/10.3389/fgene.2019.00104

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