LPM580098, a Novel Triple Reuptake Inhibitor of Serotonin, Noradrenaline, and Dopamine, Attenuates Neuropathic Pain

Background and Purpose: Sedation and somnolence remain serious adverse effects of the existing analgesics (e.g., pregabalin, duloxetine) for neuropathic pain. The available evidence indicates that serotonin (5-HT), noradrenaline (NE), and dopamine (DA) play important roles in modulating the descendi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Nannan, Li, Chunmei, Han, Rui, Wang, Yu, Yang, Mina, Wang, Hongbo, Tian, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382704/
https://www.ncbi.nlm.nih.gov/pubmed/30837867
http://dx.doi.org/10.3389/fphar.2019.00053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382704/
https://www.ncbi.nlm.nih.gov/pubmed/30837867
http://dx.doi.org/10.3389/fphar.2019.00053

Ejemplares similares