Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways

Metastasis is one of the main causes of mortality in cancer patients. Inotilone, a major component of Inonotus linteus, is a traditional Chinese medical herb. In this study, MTT results showed that inotilone had no obvious cytotoxicity. Animal model results revealed that inotilone suppressed cancer...

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Detalles Bibliográficos
Autores principales: Chao, Wei, Deng, Jeng-Shyan, Li, Pei-Ying, Kuo, Yueh-Hsiung, Huang, Guan-Jhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382761/
https://www.ncbi.nlm.nih.gov/pubmed/30787353
http://dx.doi.org/10.1038/s41598-019-38959-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382761/
https://www.ncbi.nlm.nih.gov/pubmed/30787353
http://dx.doi.org/10.1038/s41598-019-38959-z

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