A genome-wide enhancer/suppressor screen for Dube3a interacting genes in Drosophila melanogaster

The genetics underlying autism spectrum disorder (ASD) are complex. Approximately 3–5% of ASD cases arise from maternally inherited duplications of 15q11.2-q13.1, termed Duplication 15q syndrome (Dup15q). 15q11.2-q13.1 includes the gene UBE3A which is believed to underlie ASD observed in Dup15q synd...

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Detalles Bibliográficos
Autores principales: Hope, Kevin A., McGinn, Addison, Reiter, Lawrence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382765/
https://www.ncbi.nlm.nih.gov/pubmed/30787400
http://dx.doi.org/10.1038/s41598-019-38663-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382765/
https://www.ncbi.nlm.nih.gov/pubmed/30787400
http://dx.doi.org/10.1038/s41598-019-38663-y

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