Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice

Toll-like receptor 7 (TLR7) is a pattern recognition receptor that recognizes viral RNA following endocytosis of the virus and initiates a powerful immune response characterized by Type I IFN production and pro-inflammatory cytokine production. Despite this immune response, the virus causes very sig...

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Detalles Bibliográficos
Autores principales: To, Eunice E., Erlich, Jonathan, Liong, Felicia, Luong, Raymond, Liong, Stella, Bozinovski, Steven, Seow, Huei Jiunn, O’Leary, John J., Brooks, Doug A., Vlahos, Ross, Selemidis, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382773/
https://www.ncbi.nlm.nih.gov/pubmed/30787331
http://dx.doi.org/10.1038/s41598-019-38864-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382773/
https://www.ncbi.nlm.nih.gov/pubmed/30787331
http://dx.doi.org/10.1038/s41598-019-38864-5

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