Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway

MicroRNAs (miRs) play an essential role in the regulation of bone formation and homeostasis. miR-185 has been reported to negatively regulate osteogenesis in vitro. However, whether it has an impact on in vivo bone homeostasis remains unknown. Here, we demonstrated that primary osteoblasts and mesen...

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Detalles Bibliográficos
Autores principales: Cui, Qi, Xing, Jinhao, Yu, Miao, Wang, Yue, Xu, Jian, Gu, Yajuan, Nan, Xu, Ma, Wenping, Liu, Hao, Zhao, Hongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382812/
https://www.ncbi.nlm.nih.gov/pubmed/30787286
http://dx.doi.org/10.1038/s41419-019-1428-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382812/
https://www.ncbi.nlm.nih.gov/pubmed/30787286
http://dx.doi.org/10.1038/s41419-019-1428-1

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