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ZFP57 suppress proliferation of breast cancer cells through down-regulation of MEST-mediated Wnt/β-catenin signalling pathway

Activation of oncogenes by promoter hypomethylation plays an important role in tumorigenesis. Zinc finger protein 57 (ZFP57), a member of KRAB-ZFPs, could maintain DNA methylation in embryonic stem cells (ESCs), although its role and underlying mechanisms in breast cancer are not well understood. In...

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Detalles Bibliográficos
Autores principales: Chen, Lie, Wu, Xiaowei, Xie, Hui, Yao, Na, Xia, Yiqin, Ma, Ge, Qian, Mengjia, Ge, Han, Cui, Yangyang, Huang, Yue, Wang, Shui, Zheng, Mingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382817/
https://www.ncbi.nlm.nih.gov/pubmed/30787268
http://dx.doi.org/10.1038/s41419-019-1335-5