Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction

Serine hydroxymethyltransferase (SHMT) is an enzyme that catalyzes the reaction that converts serine to glycine. It plays an important role in one-carbon metabolism. Recently, SHMT has been shown to be associated with various diseases. Therefore, SHMT has attracted attention as a biomarker and drug...

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Detalles Bibliográficos
Autores principales: Nonaka, Hiroshi, Nakanishi, Yuki, Kuno, Satoshi, Ota, Tomoki, Mochidome, Kentaro, Saito, Yutaro, Sugihara, Fuminori, Takakusagi, Yoichi, Aoki, Ichio, Nagatoishi, Satoru, Tsumoto, Kouhei, Sando, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382819/
https://www.ncbi.nlm.nih.gov/pubmed/30787298
http://dx.doi.org/10.1038/s41467-019-08833-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382819/
https://www.ncbi.nlm.nih.gov/pubmed/30787298
http://dx.doi.org/10.1038/s41467-019-08833-7

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