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CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells
Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and chemokines are known to drive immune cell migration towards cancer cells. It is documented that CXCR4 signaling supports tumor metastasis formation in tissues where CXCL12, it...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382824/ https://www.ncbi.nlm.nih.gov/pubmed/30787324 http://dx.doi.org/10.1038/s41598-019-38643-2 |