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CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells
Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and chemokines are known to drive immune cell migration towards cancer cells. It is documented that CXCR4 signaling supports tumor metastasis formation in tissues where CXCL12, it...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382824/ https://www.ncbi.nlm.nih.gov/pubmed/30787324 http://dx.doi.org/10.1038/s41598-019-38643-2 |