A PKA/cdc42 Signaling Axis Restricts Angiogenic Sprouting by Regulating Podosome Rosette Biogenesis and Matrix Remodeling

Angiogenic sprouting can contribute adaptively, or mal-adaptively, to a myriad of conditions including ischemic heart disease and cancer. While the cellular and molecular systems that regulate tip versus stalk endothelial cell (EC) specification during angiogenesis are known, those systems that regu...

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Detalles Bibliográficos
Autores principales: MacKeil, J. L., Brzezinska, P., Burke-Kleinman, J., Craig, A. W., Nicol, C. J. B., Maurice, D. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382826/
https://www.ncbi.nlm.nih.gov/pubmed/30787359
http://dx.doi.org/10.1038/s41598-018-37805-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382826/
https://www.ncbi.nlm.nih.gov/pubmed/30787359
http://dx.doi.org/10.1038/s41598-018-37805-y

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