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A critical evaluation of TRPA1-mediated locomotor behavior in zebrafish as a screening tool for novel anti-nociceptive drug discovery

Current medications inadequately treat the symptoms of chronic pain experienced by over 50 million people in the United States, and may come with substantial adverse effects signifying the need to find novel treatments. One novel therapeutic target is the Transient Receptor Potential A1 channel (TRP...

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Detalles Bibliográficos
Autores principales: Ko, Mee Jung, Ganzen, Logan C., Coskun, Emre, Mukadam, Arbaaz A., Leung, Yuk Fai, van Rijn, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382835/
https://www.ncbi.nlm.nih.gov/pubmed/30787340
http://dx.doi.org/10.1038/s41598-019-38852-9