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m(6)A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine, disease treatment, and organ transplantation. As the ethical issue of human ESCs and similarity of pig in human genome and physiological characteristics, the porcine iPSCs (piPSCs) ha...

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Detalles Bibliográficos
Autores principales: Wu, Ruifan, Liu, Youhua, Zhao, Yuanling, Bi, Zhen, Yao, Yongxi, Liu, Qing, Wang, Fengqin, Wang, Yizhen, Wang, Xinxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382841/
https://www.ncbi.nlm.nih.gov/pubmed/30787270
http://dx.doi.org/10.1038/s41419-019-1417-4