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Development of unstable resistance to diminazene aceturate in Babesia bovis

Diminazene aceturate (DA) is commonly used in the treatment of bovine babesiosis caused by Babesia bovis. In this study, we attempted to develop resistance in B. bovis in vitro to DA and clofazimine (CF, a novel antibabesial agent) using short- and long-term drug pressures. In the short term, we fou...

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Detalles Bibliográficos
Autores principales: Tuvshintulga, Bumduuren, Sivakumar, Thillaiampalam, Yokoyama, Naoaki, Igarashi, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382846/
https://www.ncbi.nlm.nih.gov/pubmed/30785049
http://dx.doi.org/10.1016/j.ijpddr.2019.02.001