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Young bone marrow transplantation preserves learning and memory in old mice

Restoration of cognitive function in old mice by transfer of blood or plasma from young mice has been attributed to reduced C–C motif chemokine ligand 11 (CCL11) and β2-microglobulin, which are thought to suppress neurogenesis in the aging brain. However, the specific role of the hematopoietic syste...

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Detalles Bibliográficos
Autores principales: Das, Melanie M., Godoy, Marlesa, Chen, Shuang, Moser, V. Alexandra, Avalos, Pablo, Roxas, Kristina M., Dang, Ivy, Yáñez, Alberto, Zhang, Wenxuan, Bresee, Catherine, Arditi, Moshe, Liu, George Y., Svendsen, Clive N., Goodridge, Helen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382867/
https://www.ncbi.nlm.nih.gov/pubmed/30820468
http://dx.doi.org/10.1038/s42003-019-0298-5