Succinylation-dependent mitochondrial translocation of PKM2 promotes cell survival in response to nutritional stress

Tumor growth and progression is characteristically associated with the synergistic effects of uncontrolled cellular proliferation and cell survival under stress. Pyruvate kinase M2 (PKM2) contributes to both of these effects. However, the specific mechanism by which PKM2 promotes uncontrolled prolif...

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Detalles Bibliográficos
Autores principales: Qi, Hailong, Ning, Xianling, Yu, Chang, Ji, Xin, Jin, Yan, McNutt, Michael A., Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382874/
https://www.ncbi.nlm.nih.gov/pubmed/30787272
http://dx.doi.org/10.1038/s41419-018-1271-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382874/
https://www.ncbi.nlm.nih.gov/pubmed/30787272
http://dx.doi.org/10.1038/s41419-018-1271-9

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