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Succinylation-dependent mitochondrial translocation of PKM2 promotes cell survival in response to nutritional stress
Tumor growth and progression is characteristically associated with the synergistic effects of uncontrolled cellular proliferation and cell survival under stress. Pyruvate kinase M2 (PKM2) contributes to both of these effects. However, the specific mechanism by which PKM2 promotes uncontrolled prolif...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382874/ https://www.ncbi.nlm.nih.gov/pubmed/30787272 http://dx.doi.org/10.1038/s41419-018-1271-9 |