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Continuous culture of Escherichia coli, under selective pressure by a novel antimicrobial complex, does not result in development of resistance

We attempted to generate de novo resistance to a newly described biocidal complex, ITC (iodo-thiocyanate complex), and to levofloxacin (LVX) in Escherichia coli ATCC 25922, by means of selective chemostat culture. We measured resistance by determining the minimum inhibitory concentrations (MICs) for...

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Detalles Bibliográficos
Autores principales: Tonoyan, Lilit, Fleming, Gerard T. A., Friel, Ruairi, O’Flaherty, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382887/
https://www.ncbi.nlm.nih.gov/pubmed/30787338
http://dx.doi.org/10.1038/s41598-019-38925-9