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Construction of a germline-specific RNAi tool in C. elegans

Analysis of complex biological functions usually requires tissue-specific genetic manipulations in multicellular organisms. The C. elegans germline plays regulatory roles not only in reproduction, but also in metabolism, stress response and ageing. Previous studies have used mutants of rrf-1, which...

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Detalles Bibliográficos
Autores principales: Zou, Lina, Wu, Di, Zang, Xiao, Wang, Zi, Wu, Zixing, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382888/
https://www.ncbi.nlm.nih.gov/pubmed/30787374
http://dx.doi.org/10.1038/s41598-019-38950-8