A Dynamic Hydrophobic Core and Surface Salt Bridges Thermostabilize a Designed Three-Helix Bundle

Thermostable proteins are advantageous in industrial applications, as pharmaceuticals or biosensors, and as templates for directed evolution. As protein-design methodologies improve, bioengineers are able to design proteins to perform a desired function. Although many rationally designed proteins en...

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Detalles Bibliográficos
Autores principales: Nguyen, Catrina, Young, Jennifer T., Slade, Gabriel G., Oliveira, Ronaldo J., McCully, Michelle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382955/
https://www.ncbi.nlm.nih.gov/pubmed/30704856
http://dx.doi.org/10.1016/j.bpj.2019.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382955/
https://www.ncbi.nlm.nih.gov/pubmed/30704856
http://dx.doi.org/10.1016/j.bpj.2019.01.012

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