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Unsupervised Learning Approach for Comparing Multiple Transposon Insertion Sequencing Studies

Transposon insertion sequencing (TIS) is a widely used technique for conducting genome-scale forward genetic screens in bacteria. However, few methods enable comparison of TIS data across multiple replicates of a screen or across independent screens, including screens performed in different organism...

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Detalles Bibliográficos
Autores principales: Hubbard, Troy P., D’Gama, Jonathan D., Billings, Gabriel, Davis, Brigid M., Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382967/
https://www.ncbi.nlm.nih.gov/pubmed/30787116
http://dx.doi.org/10.1128/mSphere.00031-19