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Spatiotemporally Controlled Myosin Relocalization and Internal Pressure Generate Sibling Cell Size Asymmetry

Metazoan cells can generate unequal-sized sibling cells during cell division. This form of asymmetric cell division depends on spindle geometry and Myosin distribution, but the underlying mechanics are unclear. Here, we use atomic force microscopy and live cell imaging to elucidate the biophysical f...

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Detalles Bibliográficos
Autores principales: Pham, Tri Thanh, Monnard, Arnaud, Helenius, Jonne, Lund, Erik, Lee, Nicole, Müller, Daniel J., Cabernard, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383127/
https://www.ncbi.nlm.nih.gov/pubmed/30785031
http://dx.doi.org/10.1016/j.isci.2019.02.002