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Revealing Gene Function and Transcription Relationship by Reconstructing Gene-Level Chromatin Interaction

Chromatin is hierarchically organized in human interphase nuclei. Dynamic chromatin interactions are thought to influence gene transcription and cell fate determination. A consensus concept is that genes may form transcription factories within nucleus by spatially interaction. However, it is still n...

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Detalles Bibliográficos
Autores principales: Liu, Li, Li, Qian-Zhong, Jin, Wen, Lv, Hao, Lin, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383185/
https://www.ncbi.nlm.nih.gov/pubmed/30828411
http://dx.doi.org/10.1016/j.csbj.2019.01.011