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Revealing Gene Function and Transcription Relationship by Reconstructing Gene-Level Chromatin Interaction
Chromatin is hierarchically organized in human interphase nuclei. Dynamic chromatin interactions are thought to influence gene transcription and cell fate determination. A consensus concept is that genes may form transcription factories within nucleus by spatially interaction. However, it is still n...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383185/ https://www.ncbi.nlm.nih.gov/pubmed/30828411 http://dx.doi.org/10.1016/j.csbj.2019.01.011 |