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New Conformations of Acylation Adducts of Inhibitors of β-Lactamase from Mycobacterium tuberculosis
[Image: see text] Mycobacterium tuberculosis (Mtb), the main causative agent of tuberculosis (TB), is naturally resistant to β-lactam antibiotics due to the production of the extended spectrum β-lactamase BlaC. β-Lactam/β-lactamase inhibitor combination therapies can circumvent the BlaC-mediated res...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383187/ https://www.ncbi.nlm.nih.gov/pubmed/30632739 http://dx.doi.org/10.1021/acs.biochem.8b01085 |