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Enhancing co-translational folding of heterologous protein by deleting non-essential ribosomal proteins in Pichia pastoris
BACKGROUND: Translational regulation played an important role in the correct folding of heterologous proteins to form bioactive conformations during biogenesis. Translational pausing coordinates protein translation and co-translational folding. Decelerating translation elongation speed has been show...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383220/ https://www.ncbi.nlm.nih.gov/pubmed/30828383 http://dx.doi.org/10.1186/s13068-019-1377-z |