Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease

BACKGROUND: Epidemiologic studies strongly suggest that the pathophysiology of late-onset Alzheimer disease (AD) versus early-onset AD has environmental rather than genetic causes, thus revealing potentially novel therapeutic targets to limit disease progression. Several studies supporting the “path...

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Detalles Bibliográficos
Autores principales: Al-Atrache, Zein, Lopez, Danielle B., Hingley, Susan T., Appelt, Denah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383264/
https://www.ncbi.nlm.nih.gov/pubmed/30786875
http://dx.doi.org/10.1186/s12868-019-0489-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383264/
https://www.ncbi.nlm.nih.gov/pubmed/30786875
http://dx.doi.org/10.1186/s12868-019-0489-5

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