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Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease

BACKGROUND: To investigate how serum neurofilament light (NfL) concentration changes through the course of disease in familial Alzheimer’s disease (FAD) and to assess when NfL concentration first increases. METHODS: NfL was measured using an ultrasensitive immunoassay in 117 serum samples from 61 in...

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Detalles Bibliográficos
Autores principales: Weston, Philip S. J., Poole, Teresa, O’Connor, Antoinette, Heslegrave, Amanda, Ryan, Natalie S., Liang, Yuying, Druyeh, Ronald, Mead, Simon, Blennow, Kaj, Schott, Jonathan M., Frost, Chris, Zetterberg, Henrik, Fox, Nick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383280/
https://www.ncbi.nlm.nih.gov/pubmed/30786919
http://dx.doi.org/10.1186/s13195-019-0472-5