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Transformation of epidermal growth factor receptor T790M mutation‐positive adenosquamous carcinoma of the lung to small cell carcinoma and large‐cell neuroendocrine carcinoma following osimertinib therapy: an autopsy case report

A 59‐year‐old man with relapsed epidermal growth factor receptor (EGFR) exon 19 deletion‐positive stage IA adenosquamous carcinoma after lobectomy was treated with erlotinib and bevacizumab for 1 year followed by erlotinib alone for 1 year. Because of mediastinal and supraclavicular lymphadenopathy...

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Detalles Bibliográficos
Autores principales: Moriguchi, Shuhei, Uruga, Hironori, Fujii, Takeshi, Yasunaga, Yoichi, Takahashi, Yui, Kishi, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383305/
https://www.ncbi.nlm.nih.gov/pubmed/30828454
http://dx.doi.org/10.1002/rcr2.402