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Manipulating fenestrations in young and old liver sinusoidal endothelial cells

Fenestrations are pores within liver sinusoidal endothelial cells (LSECs) that enable the transfer of substrates (particularly insulin and lipoproteins) between blood and hepatocytes. With increasing age, there are marked reductions in fenestrations, referred to as pseudocapillarization. Currently,...

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Detalles Bibliográficos
Autores principales: Hunt, Nicholas J., Lockwood, Glen P., Warren, Alessandra, Mao, Hong, McCourt, Peter A. G., Le Couteur, David G., Cogger, Victoria C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383376/
https://www.ncbi.nlm.nih.gov/pubmed/30285464
http://dx.doi.org/10.1152/ajpgi.00179.2018