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Tyrosine Kinase Inhibitor Imatinib Mesylate Alters DMBA-Induced Early Onco/Suppressor Gene Expression with Tissue-Specificity in Mice

Tyrosine kinases play crucial roles in cellular development and tumorigenesis. Tyrosine kinase inhibitors (TKIs) are effective and widely used drug molecules in targeted cancer therapies. Altered expressions of protooncogenes and tumor suppressor genes after DMBA (7,12-dimethylbenz[a]anthracene) tre...

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Detalles Bibliográficos
Autores principales: Gergely, Péter Attila, Murnyák, Balázs, Bencze, János, Kurucz, Andrea, Varjas, Timea, Gombos, Katalin, Hortobágyi, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383434/
https://www.ncbi.nlm.nih.gov/pubmed/30882001
http://dx.doi.org/10.1155/2019/8670398