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Tyrosine Kinase Inhibitor Imatinib Mesylate Alters DMBA-Induced Early Onco/Suppressor Gene Expression with Tissue-Specificity in Mice
Tyrosine kinases play crucial roles in cellular development and tumorigenesis. Tyrosine kinase inhibitors (TKIs) are effective and widely used drug molecules in targeted cancer therapies. Altered expressions of protooncogenes and tumor suppressor genes after DMBA (7,12-dimethylbenz[a]anthracene) tre...
Autores principales: | Gergely, Péter Attila, Murnyák, Balázs, Bencze, János, Kurucz, Andrea, Varjas, Timea, Gombos, Katalin, Hortobágyi, Tibor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383434/ https://www.ncbi.nlm.nih.gov/pubmed/30882001 http://dx.doi.org/10.1155/2019/8670398 |
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