Simvastatin Improves Cardiac Hypertrophy in Diabetic Rats by Attenuation of Oxidative Stress and Inflammation Induced by Calpain-1-Mediated Activation of Nuclear Factor-κB (NF-κB)

BACKGROUND: Simvastatin, an HMG-CoA reductase inhibitor, has been reported to exert multiple protective effects on the cardiovascular system. However, the molecular mechanism remains to be examined. The present study was designed to study the effects of simvastatin on cardiac hypertrophy in diabetic...

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Detalles Bibliográficos
Autores principales: Han, Qianqian, Liu, Qianqian, Zhang, Hui, Lu, Meili, Wang, Hongxin, Tang, Futian, Zhang, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383435/
https://www.ncbi.nlm.nih.gov/pubmed/30767945
http://dx.doi.org/10.12659/MSM.913244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383435/
https://www.ncbi.nlm.nih.gov/pubmed/30767945
http://dx.doi.org/10.12659/MSM.913244

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