Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2

Matriptase is ectopically expressed in neoplastic B-cells, in which matriptase activity is enhanced by negligible expression of its endogenous inhibitor, hepatocyte growth factor activator inhibitor (HAI)-1. HAI-1, however, is also involved in matriptase synthesis and intracellular trafficking. The...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Lin, Wu, Yi-Ying, Barndt, Robert B., Yeo, Yee Hui, Lin, Yu-Wen, Sytwo, Hou-Ping, Liu, Huan-Cheng, Xu, Yuan, Jia, Bailing, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383611/
https://www.ncbi.nlm.nih.gov/pubmed/30777474
http://dx.doi.org/10.1080/14756366.2019.1577831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383611/
https://www.ncbi.nlm.nih.gov/pubmed/30777474
http://dx.doi.org/10.1080/14756366.2019.1577831

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