Cargando…

Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2

Matriptase is ectopically expressed in neoplastic B-cells, in which matriptase activity is enhanced by negligible expression of its endogenous inhibitor, hepatocyte growth factor activator inhibitor (HAI)-1. HAI-1, however, is also involved in matriptase synthesis and intracellular trafficking. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiu, Yi-Lin, Wu, Yi-Ying, Barndt, Robert B., Yeo, Yee Hui, Lin, Yu-Wen, Sytwo, Hou-Ping, Liu, Huan-Cheng, Xu, Yuan, Jia, Bailing, Wang, Jehng-Kang, Johnson, Michael D., Lin, Chen-Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383611/ https://www.ncbi.nlm.nih.gov/pubmed/30777474 http://dx.doi.org/10.1080/14756366.2019.1577831

Ejemplares similares

Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity
por: Chiu, Yi-Lin, et al.
Publicado: (2020)

Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation
por: Lai, Chih-Hsin, et al.
Publicado: (2016)

Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018)

Correction: Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin
por: Lee, Shiao-Pieng, et al.
Publicado: (2018)

Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity
por: Tseng, Chun-Che, et al.
Publicado: (2017)

N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin
por: Lai, Ying-Jung J., et al.
Publicado: (2015)

Differential Subcellular Localization Renders HAI-2 a Matriptase Inhibitor in Breast Cancer Cells but Not in Mammary Epithelial Cells
por: Chang, Hsiang-Hua D., et al.
Publicado: (2015)

The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane
por: Tseng, Chun-Che, et al.
Publicado: (2020)

Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes
por: Chen, Ya-Wen, et al.
Publicado: (2013)

Selective Inhibition of Prostasin in Human Enterocytes by the Integral Membrane Kunitz-Type Serine Protease Inhibitor HAI-2
por: Shiao, Frank, et al.
Publicado: (2017)

Decreasing the ratio of matriptase/HAI-1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer
por: Sun, Pengming, et al.
Publicado: (2016)

Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner
por: Su, Hui Chen, et al.
Publicado: (2016)

ROS is a master regulator of in vitro matriptase activation
por: Gaymon, Darius O., et al.
Publicado: (2023)

Matriptase Autoactivation Is Tightly Regulated by the Cellular Chemical Environments
por: Wang, Jehng-Kang, et al.
Publicado: (2014)

Reduced Prostasin (CAP1/PRSS8) Activity Eliminates HAI-1 and HAI-2 Deficiency–Associated Developmental Defects by Preventing Matriptase Activation
por: Szabo, Roman, et al.
Publicado: (2012)

Regulation of matriptase and HAI-1 system, a novel therapeutic target in human endometrial cancer cells
por: Sun, Pengming, et al.
Publicado: (2018)

3‐Cl‐AHPC inhibits pro‐HGF maturation by inducing matriptase/HAI‐1 complex formation
por: Ye, Fang, et al.
Publicado: (2018)

Antithrombin Regulates Matriptase Activity Involved in Plasmin Generation, Syndecan Shedding, and HGF Activation in Keratinocytes
por: Chen, Ya-Wen, et al.
Publicado: (2013)

Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM
por: Szabo, Roman, et al.
Publicado: (2023)

The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals
por: Vogel, Lotte K, et al.
Publicado: (2006)

Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane
por: Lai, Chih-Hsin, et al.
Publicado: (2016)

Human Cancer Cells Retain Modest Levels of Enzymatically Active Matriptase Only in Extracellular Milieu following Induction of Zymogen Activation
por: Chu, Li-Ling, et al.
Publicado: (2014)

Activated matriptase as a target to treat breast cancer with a drug conjugate
por: Rather, Gulam M., et al.
Publicado: (2018)

The role of TMPRSS6/matriptase-2 in iron regulation and anemia
por: Wang, Chia-Yu, et al.
Publicado: (2014)

Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer
por: Zoratti, Gina L., et al.
Publicado: (2016)

Diversity of Matriptase Expression Level and Function in Breast Cancer
por: Welman, Arkadiusz, et al.
Publicado: (2012)

The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models
por: Pomothy, Judit, et al.
Publicado: (2016)

Matriptase zymogen supports epithelial development, homeostasis and regeneration
por: Friis, Stine, et al.
Publicado: (2017)

Incidence of Healthcare-Associated Infections (HAIs) and the adherence to the HAIs’ prevention strategies in a military hospital in Alkharj
por: Ahmed, Nehad J., et al.
Publicado: (2021)

Matriptase processing of APLP1 ectodomain alters its homodimerization
por: Lanchec, Erwan, et al.
Publicado: (2020)

Health Care–Associated Infections (HAIs)
por: Almeida, Sherri-Lynne
Publicado: (2015)

Given Dimensions of Neoplastic Events as Aberrantly Operative Alternative Splicing
por: Agius, Lawrence M.
Publicado: (2009)

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1
por: Yuan, Cai, et al.
Publicado: (2011)

c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase
por: Szabo, Roman, et al.
Publicado: (2011)

Detection of Active Matriptase Using a Biotinylated Chloromethyl Ketone Peptide
por: Godiksen, Sine, et al.
Publicado: (2013)

Matriptase Deletion Initiates a Sjögren’s Syndrome-Like Disease in Mice
por: Yin, Hongen, et al.
Publicado: (2014)

Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors
por: Sales, Katiuchia Uzzun, et al.
Publicado: (2014)

Matriptase-2 deficiency protects from obesity by modulating iron homeostasis
por: Folgueras, Alicia R., et al.
Publicado: (2018)

A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2
por: Mangold, Martin, et al.
Publicado: (2018)

Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis
por: Drees, Leonard, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kcc3b6ga8ru4kl68jnrev5ovva