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Generation of a CLTA reporter human induced pluripotent stem cell line, CRMi001-A-1, using the CRISPR/Cas9 system to monitor endogenous clathrin trafficking

The most highly studied endocytic pathway, clathrin-dependent endocytosis, mediates a wide range of fundamental processes including nutrient internalization, receptor recycling, and signal transduction. In order to model tissue specific and developmental aspects of this process, CRISPR/Cas9 genomic...

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Detalles Bibliográficos
Autores principales: Anderson, Ruthellen H., Kerkvliet, Jason G., Otta, Jaelin J., Ross, Alan D., Leiferman, Patricia C., Hoppe, Adam D., Francis, Kevin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383648/
https://www.ncbi.nlm.nih.gov/pubmed/30340091
http://dx.doi.org/10.1016/j.scr.2018.10.001