Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells

The Src family of non-receptor tyrosine kinases are frequently activated in pancreatic ductal adenocarcinoma (PDAC), contributing to disease progression through downregulation of E-cadherin and induction of epithelial-to-mesenchymal transition (EMT). The purpose of this study was to examine the effi...

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Detalles Bibliográficos
Autores principales: Dosch, Austin R., Dai, Xizi, Gaidarski III, Alexander A., Shi, Chanjuan, Castellanos, Jason A., VanSaun, Michael N., Merchant, Nipun B., Nagathihalli, Nagaraj S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383685/
https://www.ncbi.nlm.nih.gov/pubmed/30800218
http://dx.doi.org/10.18632/oncotarget.26621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383685/
https://www.ncbi.nlm.nih.gov/pubmed/30800218
http://dx.doi.org/10.18632/oncotarget.26621

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