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Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells
The Src family of non-receptor tyrosine kinases are frequently activated in pancreatic ductal adenocarcinoma (PDAC), contributing to disease progression through downregulation of E-cadherin and induction of epithelial-to-mesenchymal transition (EMT). The purpose of this study was to examine the effi...
Autores principales: | Dosch, Austin R., Dai, Xizi, Gaidarski III, Alexander A., Shi, Chanjuan, Castellanos, Jason A., VanSaun, Michael N., Merchant, Nipun B., Nagathihalli, Nagaraj S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383685/ https://www.ncbi.nlm.nih.gov/pubmed/30800218 http://dx.doi.org/10.18632/oncotarget.26621 |
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