LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer

Cancer stem cells (CSCs), which play important roles in tumor initiation and progression, are resistant to many types of therapies. However, the regulatory mechanisms underlying CSC-specific properties, including self-renewal, are poorly understood. Here, we found that LATS1/2, the core Hippo pathwa...

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Detalles Bibliográficos
Autores principales: Nozaki, Masami, Yabuta, Norikazu, Fukuzawa, Moe, Mukai, Satomi, Okamoto, Ayumi, Sasakura, Towa, Fukushima, Kohshiro, Naito, Yoko, Longmore, Gregory D., Nojima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383686/
https://www.ncbi.nlm.nih.gov/pubmed/30800215
http://dx.doi.org/10.18632/oncotarget.26583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383686/
https://www.ncbi.nlm.nih.gov/pubmed/30800215
http://dx.doi.org/10.18632/oncotarget.26583

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