Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo

EMT occurs in response to a number of stresses conditions as mechanical stretch, cancer, hypoxia, oxidative stress (ROS), among others. EMT describes a phenotypical change induced in epithelial cells. It is characterized by increases in motility, extracellular matrix synthesis, proliferation, and in...

Descripción completa

Detalles Bibliográficos
Autores principales: Convento, Marcia, Pessoa, Edson, Aragão, Alef, Schor, Nestor, Borges, Fernanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383687/
https://www.ncbi.nlm.nih.gov/pubmed/30800221
http://dx.doi.org/10.18632/oncotarget.26634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383687/
https://www.ncbi.nlm.nih.gov/pubmed/30800221
http://dx.doi.org/10.18632/oncotarget.26634

Ejemplares similares