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Repurposing old carbon monoxide-releasing molecules towards the anti-angiogenic therapy of triple-negative breast cancer

Triple-negative breast cancer (TNBC) is defined by the lack of expression of the oestrogen and progesterone receptors and HER-2. Recently, carbon monoxide (CO) was found to behave as an important endogenous signalling molecule and to suppress VEGF receptor-2 (VEGFR-2) and protein kinase B phosphoryl...

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Detalles Bibliográficos
Autores principales: Kourti, Malamati, Westwell, Andrew, Jiang, Wen, Cai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383690/
https://www.ncbi.nlm.nih.gov/pubmed/30800223
http://dx.doi.org/10.18632/oncotarget.26638