Deoxyribonuclease I Activity, Cell-Free DNA, and Risk of Liver Cancer in a Prospective Cohort

BACKGROUND: Circulating cell-free DNA (cfDNA) is a proposed latent biomarker for several cancers, including liver cancer. Deoxyribonucleases (DNases) facilitate the timely and efficient degradation of cfDNA, leading us to hypothesize that DNase I and/or II might be a more sensitive early biomarker t...

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Detalles Bibliográficos
Autores principales: Golonka, Rachel M, Yeoh, Beng San, Petrick, Jessica L, Weinstein, Stephanie J, Albanes, Demetrius, Gewirtz, Andrew T, McGlynn, Katherine A, Vijay-Kumar, Matam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383694/
https://www.ncbi.nlm.nih.gov/pubmed/30815627
http://dx.doi.org/10.1093/jncics/pky083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383694/
https://www.ncbi.nlm.nih.gov/pubmed/30815627
http://dx.doi.org/10.1093/jncics/pky083

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